Cloxabiotic

Cloxabiotic

cloxacillin

Manufacturer:

KAPL

Distributor:

Averroes Pharma
Concise Prescribing Info
Contents
Cloxacillin Na
Indications/Uses
Skin & soft tissue infections caused by pneumococci; upper & lower resp tract infection.
Dosage/Direction for Use
Adult 250 mg IM every 4-6 hr or 500 mg IV over 3-4 min every 4-6 hr. Childn 2-10 yr ½ adult dose. Infant up to 2 yr ¼ adult dose.
Contraindications
Hypersensitivity to penicillins. Not to be used for infections due to penicillinase-producing organisms.
Special Precautions
Hypersensitivity to penicillins. Not to be given in patients w/ infectious mononucleosis. Risk of Jarisch-Herxheimer in patients w/ syphilis. High-dose use. Severe renal impairment (CrCl <10 mL/min). Lactation.
Adverse Reactions
Nausea, diarrhea, digestive disorders; maculopapular exanthema; haemolytic anemia, neutropenia; convulsion. Jarisch-Herxheimer reactions.
Drug Interactions
Substantial mutual inactivation w/ aminoglycosides. Higher serum peak conc & prolonged serum conc w/ probenecid. Increased risk of skin rash w/ allopurinol. Prolonged &/or worsened diarrhea w/ antiperistaltic antidiarrheals. Interfered bactericidal effects by chloramphenicol, erythromycin, sulfonamides, tetracyclines. Decreased effectiveness of OCs.
MIMS Class
ATC Classification
J01CF02 - cloxacillin ; Belongs to the class of beta-lactamase resistant penicillins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Cloxabiotic powd for inj 250 mg
Packing/Price
10 × 1's;50 × 1's
Form
Cloxabiotic powd for inj 500 mg
Packing/Price
10 × 1's;50 × 1's
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