Dexilant Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Dexlansoprazole

Indications/Uses

Healing of erosive esophagitis (EE). Maintenance of healed EE & relief of heartburn. Heartburn associated w/ symptomatic non-erosive GERD.

Click to view Dexilant detailed prescribing information

Dosage/Direction for Use

Patient ≥12 yr Healing of EE 60 mg once daily for up to 8 wk. Symptomatic non-erosive GERD 30 mg once daily for 4 wk. Maintenance of healed EE & relief of heartburn Adult 30 mg once daily for up to 6 mth. Adolescent 12-17 yr 30 mg once daily for up to 4 mth.

Click to view Dexilant detailed prescribing information

Overdosage

View Dexilant overdosage for action to be taken in the event of an overdose.

Administration

May be taken with or without food: Swallow whole, do not chew. For patients w/ swallowing difficulties, open cap & empty contents in 20 mL water. The dispersion may be administered in an oral syringe or via a nasogastric tube (>16 French).

Contraindications

Hypersensitivity.

Click to view Dexilant detailed prescribing information

Special Precautions

Discontinue use if severe cutaneous lupus erythematosus occurs. Gastric malignancy. Increased risk of Clostridium difficile-associated diarrhea; osteoporosis-related hip, wrist or spine fractures. Severe hypomagnesaemia; subacute cutaneous lupus erythematosus. Vit B₁₂ malabsorption due to hypo- or achlorhydria. Ensure adequate intake of vit D & Ca. Long-term & high-dose use. Discontinue use at least 5 days prior to chromogranin A measurements. Concomitant use w/ high-dose MTX; digoxin or drugs causing hypomagnesemia eg, diuretics. Severe hepatic impairment. Pregnancy & lactation. Childn <12 yr.

Click to view Dexilant detailed prescribing information

Use In Pregnancy & Lactation

Click to view Dexilant detailed prescribing information

Adverse Reactions

Diarrhea, abdominal pain, nausea, URTI, vomiting, flatulence.

Click to view Dexilant detailed prescribing information

Drug Interactions

Decreased systemic conc of HIV PIs eg, atazanavir, nelfinavir. Interfered w/ absorption of ampicillin esters, digoxin, Fe salts, ketoconazole. Increased INR & prothrombin time w/ warfarin. Increased whole blood levels of tacrolimus. Elevated & prolonged serum levels of MTX &/or hydroxymethotrexate.

Click to view Dexilant detailed prescribing information

Storage

View Dexilant storage conditions for details to ensure optimal shelf-life.

Description

View Dexilant description for details of the chemical structure and excipients (inactive components).

Action

View Dexilant mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antacids, Antireflux Agents & Antiulcerants

ATC Classification

A02BC06 - dexlansoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).

Regulatory Classification

Presentation/Packing

Form

Dexilant DR cap 30 mg

Packing/Price

14's;7's

Form

Dexilant DR cap 60 mg

Packing/Price

14's;7's

Dexilant

dexlansoprazole

Manufacturer:

Takeda

Distributor:

Zuellig Pharma