Monitor for acute/chronic urinary retention in patients w/ large residual urinary vol &/or severely impaired urine flow. Perform digital rectal exam & prostate-specific antigen level for prostate cancer detection. Changes in breast tissue eg, lumps or nipple discharge; male breast cancer. CHD, orthostatic hypotension; patients w/ excessive haemodynamic reaction on previous α1
-blocker treatment & receiving antihypertensives; swallowing disorders eg, stenosing oesophageal changes or neurological disorders accompanied by impaired oesophageal motility. Intraoperative floppy iris syndrome (IFIS). Co-administration w/ CYP3A4 inhibitors. May impair ability to drive & use machines. Mild to moderate hepatic & severe renal impairment. Not to be used during pregnancy & potential pregnancy. Lactation. Not to be used in patients ≤21 yr.