Not to be used interchangeably w/ other LMWH during ongoing treatment. Heparin-induced thrombocytopenia. Increased risk of bleeding eg, severe arterial HTN, history of peptic ulceration or other organic lesion likely to bleed, vascular chorioretinal disorder; post-op brain, spinal cord or eye surgery; spinal/epidural anaesth/spinal lumbar puncture; cutaneous necrosis. Patients w/ raised plasma K or at risk of increased plasma K levels eg, patients w/ DM, pre-existing metabolic acidosis. Frequently monitor signs & symptoms of neurological impairment. Monitor platelet counts throughout course of treatment. May cause severe allergic reaction due to latex. Concomitant use w/ drugs causing hyperkalemia eg, ACE inhibitors, NSAIDs; platelet inhibitors, other anticoagulants; aspirin, other salicylates. Renal impairment; chronic renal failure. Hepatic impairment. Pregnancy. Not to be used during lactation. Elderly.