HTN 50 mg once daily, may be increased to 100 mg as single or 2 divided doses.
Intravascular vol-depletion eg, patient treated w/ high-dose diuretics Initially 25 mg once daily.
HTN w/ left ventricular hypertrophy Initially 50 mg once daily w/ low-dose hydrochlorothiazide, may be increased to 100 mg once daily based on BP response.
Renal protection in type 2 diabetic patient w/ proteinuria & HTN Initially 50 mg once daily, may be increased to 100 mg once daily based on BP response.