Cap: Symptomatic treatment of acute diarrhoea in adults when causal treatment is not possible. Granules for oral susp: Complementary symptomatic treatment of acute diarrhoea in infants >3 mth & childn together w/ oral rehydration.
Adult cap Adult Initially 1 cap, then 1 cap tds. Treatment: Not >7 days. Childn granules for oral susp Childn >27 kg Two 30-mg sachets tds, childn 13-27 kg One 30-mg sachet tds, childn ≥13 kg 1.5 mg/kg/dose (1-2 sachets tds). Infant granules for oral susp Infant 9-13 kg Two 10-mg sachets tds, infant <9 kg One 10-mg sachet tds; childn <13 kg 1.5 mg/kg/dose (1-2 sachets tds). Treatment: Not >7 days.
May be taken with or without food: Cap: Take preferably before the main meals. Granules for oral susp: May be mixed w/ food or dispersed in a glass of water or into a feeding-bottle. Mix thoroughly & take immediately after prep.
Hypersensitivity. Concomitant use of ACE inhibitors (eg, captopril, enalapril, lisinopril, perindopril, ramipril) in patients w/ angioedema. Fructose intolerance, glucose-galactose malabsorption syndrome or sucrose-isomaltase insufficiency.
Discontinue use if severe skin reactions occur. Not to be used in presence of bloody or purulent stools, fever & other severe disease; prolonged or uncontrolled vomiting. Not recommended in chronic & antibiotic-associated diarrhoea. History of angioedema unrelated to therapy. Ensure adequate fluid intake. Not recommended in long-term treatment. Not to be taken by patients w/ galactose & fructose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption or sucrose-isomaltase insufficiency. Hepatic or renal impairment. Not to be used during pregnancy & lactation. Not to be used in childn w/ renal or hepatic impairment; infants <3 mth.