Levophed

Levophed

norepinephrine

Manufacturer:

Pfizer

Distributor:

DKSH
Concise Prescribing Info
Contents
Norepinephrine bitartrate
Indications/Uses
BP control in acute hypotensive states. Adjunctive treatment in cardiac arrest & profound hypotension.
Dosage/Direction for Use
Initially 2-3 mL/min via IV infusion. Maintenance: 0.5-1 mL/min.
Contraindications
Hypersensitivity. Concomitant use w/ halothane anesth.
Special Precautions
Discontinue use if extravasation occurs. Coronary, mesenteric or peripheral vascular thrombosis; patients w/ hypotension following MI; Prinzmetal's variant angina, diabetes, HTN or hyperthyroidism. Profound hypoxia or hypercabia. Frequently check BP & rate of flow to avoid HTN. Avoid abrupt w/drawal. Prolonged use. Concomitant use w/ MAOIs or TCAs. May affect ability to drive & use machines. Pregnancy & lactation. Not recommended in childn. Elderly.
Adverse Reactions
Anxiety; headache; cardiogenic shock, arrhythmia, bradycardia, stress cardiomyopathy; peripheral ischemia, gangrene, HTN, plasma depletion; dyspnea; inj site extravasation & necrosis.
Drug Interactions
Severe, prolonged HTN & possible arrhythmias w/ volatile halogenated anesth agents, MAOIs, TCAs, linezolid, adrenergic-serotoninergic drugs or other cardiac sensitizing agents. Enhanced effects of guanethidine.
MIMS Class
ATC Classification
C01CA03 - norepinephrine ; Belongs to the class of adrenergic and dopaminergic cardiac stimulants excluding glycosides. Used in the treatment of hypotension.
Presentation/Packing
Form
Levophed inj 1 mg/mL
Packing/Price
4 mL x 10 × 1's
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