Lodoxamide


Concise Prescribing Info
Indications/Uses
Allergic conjunctivitis.
Dosage/Direction for Use
Adult : Ophth As 0.1% soln: Instill 1-2 drops into affected eye(s) 4 times/day.
Dosage Details
Ophthalmic
Allergic conjunctivitis
Adult: As 0.1% soln: Instill 1-2 drops into affected eye(s) 4 times daily.
Child: ≥4 yr Same as adult dose.
Special Precautions
Childn. Pregnancy and lactation.
Adverse Reactions
Significant: Eye irritation (e.g. burning, stinging, discomfort), blurred vision or visual disturbances.
Nervous: Headache, dizziness, drowsiness, somnolence.
GI: Nausea, stomach discomfort.
Resp: Dry nose, sneezing.
Ophthalmologic: Eye itching, foreign body sensation of eye, dry eye, crystalline eye deposit, lacrimation, ocular hyperaemia, ocular oedema, xerophthalmia, asthenopia, blepharitis, chemosis, corneal abrasion, corneal erosion, corneal ulcer, epitheliopathy, eye pain, keratitis, ocular warming sensation, swelling of eye.
Dermatologic: Skin rash.
Patient Counseling Information
This drug may cause temporary blurred vision or visual disturbances, if affected, do not drive or operate machinery. Remove contact lenses prior to ophth admin and reinsert after 15 min.
Action
Description: Lodoxamide is a mast cell stabiliser that inhibits release and activation of inflammatory mediators (e.g. histamine, leukotrienes) from conjunctival tissues thus inhibiting type 1 immediate hypersensitivity reactions.
Pharmacokinetics:
Excretion: Mainly via urine, 83%. Elimination half-life: 8.5 hr.
Chemical Structure

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Storage
Store below 25°C. Do not freeze.
ATC Classification
S01GX05 - lodoxamide ; Belongs to the class of other ophthalmologic antiallergics.
Disclaimer: This information is independently developed by MIMS based on Lodoxamide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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