Not for protection against HIV infection or other STDs. Discontinue use if deterioration of DM or tendency towards DM, HTN, varicose veins, history of phlebitis & clinical depression, otosclerosis, multiple sclerosis, migraine, epilepsy, porphyria, tetany, chorea, SLE, obesity, family history of breast cancer & patient history of breast nodules, conditions aggravated by fluid retention. Venous & arterial thrombosis & thromboembolism. Ocular lesions, increased BP, breast & cervical cancer; gallbladder disease; hepatitis C; migraine/headache; angioedema; depressed serum folate levels; vomiting/diarrhea; impaired glucose tolerance or DM; genital bleeding, depression. Smoking. Perform breast, liver, extremities & pelvic organ exam, pap smear prior to therapy. Avoid prolonged exposure to sun. Contact lens users. Long-term therapy w/ hepatic enzyme inducers. Hepatic neoplasia/liver disease. Discontinue use in cholestasis recurrence, acute or chronic hepatic function disturbances; renal dysfunction. Not indicated in premenarche & postmenopausal women. Not to be used during pregnancy. Not recommended during lactation. Not for premenarche & postmenopausal women.