Monem

Monem

meropenem

Manufacturer:

Biolab

Distributor:

Medispec
Concise Prescribing Info
Contents
Meropenem trihydrate
Indications/Uses
Pneumonias including hospital acquired pneumonias, UTI, intra-abdominal infections, gynaecological infections eg, endometritis & pelvic inflammatory disease, bacterial meningitis, septicaemia. Monotherapy or in combination w/ antiviral or antifungal agents as empiric treatment of presumed infections w/ febrile neutropenia.
Dosage/Direction for Use
Adult Pneumonia, UTI, gynaecological, skin & skin structure infections 500 mg 8 hrly. Nosocomial pneumonias, peritonitis, presumed infections in febrile neutropenic patient, septicaemia 1 g 8 hrly. Meningitis 2 g 8 hrly. Childn >3 mth & up to 12 yr 10-20 mg/kg 8 hrly, >50 kg Adult dosage. Meningitis 40 mg/kg 8 hrly. Febrile episodes in neutropenic patient 20 mg/kg 8 hrly. All doses are to be administered via IV bolus inj over 5 min or IV infusion over 15-30 min.
Contraindications
Special Precautions
History of hypersensitivity to β-lactam antibiotics. Not recommended in methicillin-resistant Staph infections. Prolonged use. Antibiotic-associated diarrhea; pseudomembranous colitis. Concomitant use w/ nephrotoxic drugs. Monitor transaminase & bilirubin levels in patients w/ hepatic disease. Renal insufficiency. Not to be used during pregnancy & lactation.
Adverse Reactions
Local reactions at inj site; urticaria, rash, pruritus, erythema multiforme, toxic epidermal necrolysis & Stevens-Johnson syndrome; GI disturbances, pseudomembranous colitis; hematological & hepatic changes; paraesthesiae, headache, seizures; oral & vag candidosis.
Drug Interactions
Decreased renal excretion w/ probenecid. Reduced valproic acid serum levels to subtherapeutic levels.
MIMS Class
ATC Classification
J01DH02 - meropenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.
Presentation/Packing
Form
Monem powd for inj/infusion 500 mg
Packing/Price
10 × 1's
Form
Monem powd for inj/infusion 1 g
Packing/Price
10 × 1's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in