Moxifloxacin tablets are indicated for the treatment of adults (> 18 years of age) with the following bacterial infections caused by susceptible strains: Acute sinusitis*; Acute exacerbations of chronic bronchitis*; Community acquired pneumonia; Mild to moderately severe inflammatory pelvic diseases (i.e. Infections of the upper female genital tract, including salpingitis and endometritis), without an associated tubo-ovarian or pelvic abscess.
Moxifloxacin 400 mg film-coated tablets are not recommended for monotherapy of mild to moderately severe inflammatory pelvic diseases. Preferably, they should be administered in combination with another suited antibiotic (such as cephalosporin), due to the increasing resistance of Neisseria gonorrhoeae to moxifloxacin; that is, unless moxifloxacin-resistant Neisseria gonorrhoeae can be ruled out: Complicated skin and skin structure infections; Complicated intra-abdominal infections including polymicrobial infections such as abscesses.
*Moxifcin film coated tablet 400mg should be only used: When Pseudomonas is considered AND the patient is allergic to antipseudomonal penicillins/cephalosporins; For resistant organisms with no other alternative antibiotics available.
Consideration should be given to official guidance on the appropriate use of antibacterial agents.