Not indicated in exogenous hypertiglyceridaemia (type 1 hyperchylomicronaemia). Patients w/ bleeding disorders, at high risk of hemorrhage due to severe trauma, surgery. Monitor ALAT & ASAT levels regularly in particular w/ high dosage (ie, 4 cap). Concomitant use w/ anticoagulant therapy or other drugs affecting coagulation eg, ASA or NSAIDs. Renal & hepatic impairment. Not to be used during pregnancy & lactation. Childn. Elderly >70 yr.