Increased risk of MI, pulmonary embolism, invasive breast & ovarian cancer. CV risk, stroke, venous thromboembolism; endometrial, breast & ovarian cancer; dementia, gallbladder disease, hypercalcemia, palliative therapy in men, angioedema, fluid retention, hypertriglyceridemia, elevated BP, exacerbation of asthma, epilepsy, migraine w/ or w/o aura, otosclerosis, porphyria, SLE, hepatic hemangiomas, endometriosis; hypocalcemia, hypothyroidism; impaired glucose tolerance. History of cholestatic jaundice. Hepatic impairment. Not to be used during pregnancy & lactation. Childn. Elderly >65 yr.