Pulmicort

Pulmicort

budesonide

Manufacturer:

AstraZeneca

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Budesonide
Indications/Uses
Bronchial asthma. Respules: Acute laryngotracheobronchitis (croup) in infants & childn.
Dosage/Direction for Use
Respules Bronchial asthma Adult Initially 1-2 mg bd. Maintenance: 0.5-1 mg bd. Childn Initially 0.5-1 mg bd. Maintenance: 0.25-0.5 mg bd. Croup Infant & childn 2 mg as single dose or 2 1-mg dose separated by 30 min, every 12 hr up to 36 hr or until improvement. Turbuhaler Adult 200-800 mcg daily in 2-4 divided doses. Severe cases Up to 1,600 mcg. Childn ≥7 yr 100-800 mcg daily in 2-4 divided doses, 5-7 yr 100-400 mcg daily in 2-4 divided doses.
Contraindications
Special Precautions
Active or quiescent pulmonary TB; fungal or viral airway infections. Pneumonia in patients w/ COPD. Cushing's syndrome, Cushingoid features, adrenal suppression, decreased bone mineral density, cataract, glaucoma, psychomotor hyperactivity, sleep disorders, anxiety, depression or aggression. Periods of stress, severe asthma attack or elective surgery. Transferring from oral steroids. High-dose & prolonged use. Avoid concomitant use w/ CYP3A4 inhibitors eg, ketoconazole, itraconazole or HIV PIs. Hepatic impairment. Pregnancy. Growth retardation in childn & adolescents. Respules: Not indicated for rapid relief of bronchospasm. Not suitable as sole therapy for status asthmaticus or other acute asthma exacerbations. Bacterial airway infections. Not to be used w/ positive pressure delivering systems. Lactation. Turbuhaler: Not intended for rapid relief of acute asthma episodes. Discontinue use if paradoxical bronchospasm occurs. Oral candidiasis; visual disturbances. Severe liver cirrhosis.
Adverse Reactions
Oral candidiasis; pneumonia (COPD patients); cough; throat irritation. Respules: Hoarseness, sore throat, tongue & mouth irritation, dry mouth. Turbuhaler: Throat candidiasis.
Drug Interactions
Increased systemic exposure w/ CYP3A4 inhibitors eg, ketoconazole, itraconazole, HIV PIs. Turbuhaler: Increased plasma conc & corticosteroid effects w/ oestrogens, contraceptive steroids. False results w/ ACTH stimulation test.
MIMS Class
Antiasthmatic & COPD Preparations
ATC Classification
R03BA02 - budesonide ; Belongs to the class of other inhalants used in the treatment of obstructive airway diseases, glucocorticoids.
Presentation/Packing
Form
Pulmicort respules 0.25 mg/mL
Packing/Price
30 × 1's
Form
Pulmicort respules 0.5 mg/mL
Packing/Price
30 × 1's
Form
Pulmicort turbuhaler 100 mcg/dose
Packing/Price
200 dose x 1's
Form
Pulmicort turbuhaler 200 mcg/dose
Packing/Price
100 dose x 1's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in