Individualized dosage. Type 1 DM Once daily w/ short-/rapid-acting insulin & requires individual dose adjustments. Type 2 DM Initially 0.2 units/kg followed by individual dose adjustments, may be given w/ other antihyperglycaemic products.
Not to be administered IV, not to be used in insulin infusion pumps. Not for diabetic ketoacidosis. Patients w/ significant coronary arteries stenoses or blood vessels supplying the brain (risk of cardiac or cerebral complications of hypoglycaemia), proliferative retinopathy; patients in whom glycaemic control is markedly improved, whom hypoglycaemia develops gradually & whom an autonomic neuropathy is present, after transfer from animal insulin to human insulin, long history of diabetes, suffering from a psychiatric illness, receiving concurrent treatment w/certain other medicinal products; change in the inj area, improved insulin sensitivity (eg, removal of stress factors), unaccustomed, increased or prolonged physical activity, intercurrent illness (eg, vomiting, diarrhoea), inadequate food intake, missed meals, alcohol consumption, certain uncompensated endocrine disorders (eg, hypothyroidism & anterior pituitary or adrenocortical insufficiency); switching between & from other insulins. Combination w/ pioglitazone. May affect ability to drive & use machines. Lactation. Childn <18 yr. Elderly.
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