Individualized dosage. Type 1 DM Once daily w/ short-/rapid-acting insulin & requires individual dose adjustments. Type 2 DM Initially 0.2 u/kg followed by individual dose adjustments, may be given w/ other antihyperglycaemic products.
Not to be administered IV, not to be used in insulin infusion pumps. Not for diabetic ketoacidosis. Patients w/ significant coronary arteries stenosis or blood vessels supplying the brain, proliferative retinopathy; patients in whom glycaemic control is markedly improved, hypoglycaemia develops gradually & autonomic neuropathy is present, after transfer from animal to human insulin, long history of diabetes, suffering from psychiatric illness, receiving concurrent treatment w/certain other medicinal products; change in the inj area, improved insulin sensitivity (eg, removal of stress factors), unaccustomed, increased or prolonged physical activity, intercurrent illness (eg, vomiting, diarrhoea), inadequate food intake, missed meals, alcohol consumption, certain uncompensated endocrine disorders (eg, hypothyroidism & anterior pituitary or adrenocortical insufficiency); switching between & from other insulins. Formation of insulin Ab. Combination w/ pioglitazone. May affect ability to drive & use machines. Lactation. Childn <6 yr. Elderly ≥65 yr.
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