Vasoten Dosage & Drug Information

Concise Prescribing Info

Contents

Bisoprolol fumarate

Indications/Uses

Management of HTN & angina pectoris.

Dosage/Direction for Use

HTN/angina pectoris Initially 5 mg once daily, may be increased to 10 mg once daily. Max: 20 mg once daily. Stable chronic heart failure 1.25 mg once daily for 1 wk, if well tolerated increase dose to 2.5 mg once daily for a further wk, then increase to 3.75 mg once daily for a further wk, then increase to 5 mg once daily for the following 4 wk, then increase to 7.5 mg once daily for the following 4 wk, then increase to 10 mg once daily for maintenance treatment. Max: 10 mg once daily.

Administration

May be taken with or without food.

Contraindications

Untreated cardiac failure, cardiogenic shock, SA block, 2nd/3rd degree AV block, marked bradycardia, severe asthma, sick sinus syndrome, hypotension, severe peripheral circulatory disturbances, untreated tumours of the adrenal gland (phaeochromocytoma), metabolic acidosis.

Special Precautions

Do not stop treatment abruptly. DM w/ extremely fluctuating blood glucose levels, strict fasting, ongoing desensitisation therapy, 1st degree AV block, Prinzmetal's angina, peripheral arterial occlusive disease, history of psoriasis, asthma or chronic obstructive airway disease; thyrotoxicosis, general anesth. Patients w/ prolonged PR conduction interval, poor cardiac reserve & Raynaud's syndrome. Severe renal & hepatic impairment. Pregnancy & lactation.

Adverse Reactions

Bradycardia, worsening of heart failure, dizziness, headache, GI disturbances, coldness or numbness in the extremities, hypotension, asthenia, fatigue.

View ADR Monitoring Form

Drug Interactions

Class I & III antiarrhythmics; verapamil, nifedipine; centrally-acting antihypertensives, topical β-blockers, parasympathomimetics, insulin or oral antidiabetics, anesth, cardiac glycosides, NSAIDs, β-sympathomimetics; sympathomimetics that activate both β- & α-adrenoceptors; TCAs, barbiturates, phenothiazines; mefloquine, MAOIs.

MIMS Class

Beta-Blockers

ATC Classification

C07AB07 - bisoprolol ; Belongs to the class of selective beta-blocking agents. Used in the treatment of cardiovascular diseases.

Regulatory Classification

Presentation/Packing

Form

Vasoten film-coated tab 5 mg

Packing/Price

10 × 10's

Vasoten

bisoprolol

Manufacturer:

Synmosa

Distributor:

Apex