Adivast

Adivast

atorvastatin

Manufacturer:

Medhaus

Distributor:

Medhaus
Concise Prescribing Info
Contents
Atorvastatin Ca
Indications/Uses
Reduces LDL-cholesterol, apolipoprotein B & triglycerides; & increases HDL-cholesterol in the treatment of hyperlipidaemias including hypercholesterolaemias & combined (mixed) hyperlipidaemias (type IIa or IIb hyperlipoproteinaemias), hypertriglyceridaemia & dysbetalipoproteinaemia. Adjunctive therapy in patients w/ homozygous familial hypercholesterolaemia who have some LDL-receptor function.
Dosage/Direction for Use
Initially 10-20 mg daily, may be adjusted at intervals of 4 wk up to max of 80 mg daily.
Administration
May be taken with or without food: Avoid excessive consumption (>1 L/day) of grapefruit juice.
Contraindications
Active liver disease or unexplained persistently raised serum aminotransferase conc. Pregnancy & lactation.
Special Precautions
Discontinue use if marked or persistent increased serum aminotransferase conc & creatine phosphokinase occur or if myopathy is diagnosed. Patients at risk of rhabdomyolysis particularly those who are taking drugs that increase plasma conc of statin. Severe renal impairment.
Adverse Reactions
GI disturbances; headache, skin rashes, dizziness, blurred vision, insomnia, dysgeusia; reversible increases in serum-aminotransferase conc; hepatitis, pancreatitis; hypersensitivity reactions including anaphylaxis & angioedema; myopathy (characterized by myalgia & muscle weakness & associated w/ increased creatine phosphokinase conc).
Drug Interactions
Development of myopathy & rhabdomyolysis w/ other statins. Increased risk of myopathy w/ fibric acid derivatives (fibrates or gemfibrozil), nicotinic acid. Simvastatin, lovastatin; ciclosporin, itraconazole, ketoconazole, erythromycin, clarithromycin, HIV-PIs, nefazodone, amiodarone, verapamil; grapefruit juice.
ATC Classification
C10AA05 - atorvastatin ; Belongs to the class of HMG CoA reductase inhibitors. Used in the treatment of hyperlipidemia.
Presentation/Packing
Form
Adivast FC tab 20 mg
Packing/Price
30's (P600/box)
Form
Adivast FC tab 40 mg
Packing/Price
24's (P624/box)
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