Anastro-cell

Anastro-cell

anastrozole

Manufacturer:

Cell Pharm

Distributor:

Croma Medic

Marketer:

Detoxicare
Concise Prescribing Info
Contents
Anastrozole
Indications/Uses
Advanced or locally advanced breast cancer & as adjuvant treatment in early breast cancer.
Dosage/Direction for Use
Adult including elderly 1 mg once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Estrogen-containing therapies & tamoxifen. Moderate or severe hepatic disease. Severe renal impairment (CrCl <20 mL/min). Premenopausal women. Pregnancy & lactation.
Special Precautions
Not to be used in childn w/ growth hormone deficiency in addition to growth hormone treatment. Women w/ osteoporosis; assessment of bone mineral density at the commencement of treatment & at regular intervals thereafter. Concomitant use w/ LH-releasing hormone analogues. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. May affect ability to drive & use machines. Not recommended for childn & adolescent.
Adverse Reactions
Headache, hot flushes, nausea, rash, joint pain/stiffness & asthenia. Anorexia, hypercholesterolemia, somnolence, carpal tunnel syndrome, diarrhea, vomiting, increase in alkaline phosphatase/ALT/AST; alopecia, allergic reaction, bone pain & vag dryness.
Drug Interactions
Pharmacological action may be antagonized w/ estrogen-containing therapies & diminshed w/ tamoxifen.
ATC Classification
L02BG03 - anastrozole ; Belongs to the class of enzyme inhibitors. Used in treatment of neoplastic diseases.
Presentation/Packing
Form
Anastro-cell FC tab 1 mg
Packing/Price
30's
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