atracurium besilate




Endure Medical
Concise Prescribing Info
Atracurium besilate
Adjunct to general anesth to enable tracheal intubation, relax muscles during surgery or controlled ventilation.
Dosage/Direction for Use
Adult & childn Initially 300-600 mcg/kg by IV inj. Subsequently 80-200 mcg/kg after 15-25 min. Patient w/ CV disease Initial dose to be administered over a period of 60 sec. May also be given by continuous infusion at a rate of 5-10 mcg/kg/min to maintain neuromuscular block during prolonged procedures.
Special Precautions
Assist or control resp until atracurium is inactivated or antagonized. Resp insufficiency or pulmonary disease, neuromuscular disorders. Dehydrated or severely ill patients. History of asthma & hypersensitivity to any neuromuscular blocker.
Adverse Reactions
Tachycardia, increased BP; reduced GI motility & tone, wheal-&-flare at inj site, flushing. Occasionally, bronchospasm. Rarely, anaphylactoid reactions, malignant hyperthermia.
Drug Interactions
Anticholinesterase; lidocaine, procainamide, quinidine, verapamil; aminoglycosides, lincosamides, polymyxins & tetracyclines.
ATC Classification
M03AC04 - atracurium ; Belongs to the class of other quaternary ammonium-containing agents used as peripherally-acting muscle relaxants.
Atracor soln for inj 10 mg/mL
2.5 mL x 10 × 1's
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