Bestatin

Bestatin

atorvastatin

Manufacturer:

Umedica Labs

Distributor:

Littman
Concise Prescribing Info
Contents
Atorvastatin Ca
Indications/Uses
Reduce LDL-cholesterol, apolipoprotein B & increase HDL-cholesterol in the treatment of hyperlipidemias including hypercholesterolemias & combined hyperlipidemia, hypertriglyceridemia & dysbetalipoproteinemia. Adjunctive therapy in patients w/ homozygous familial hypercholesterolemia who have some LDL-receptor function.
Dosage/Direction for Use
Usual dose: 10-20 mg once daily. Patient requiring large reduction in LDL-cholesterol Initially 40 mg daily. Dose may be adjusted at 4-wk intervals up to a max of 80 mg daily. Childn & adolescent 10-17 yr w/ heterozygous familial hypercholesterolemia Initially 10 mg once daily, adjusted to a max of 20 mg once daily.
Administration
May be taken with or without food: Avoid excessive consumption (>1 L/day) of grapefruit juice.
Contraindications
Acute liver disease or unexplained persistently raised serum aminotransferase conc.
Special Precautions
Assess liver functions before treatment & monitor periodically 1 yr after the last dose elevation. Patients w/ severe renal impairment. Risk of reversible increases in serum aminotransferase conc. Pregnancy.
Adverse Reactions
GI disturbances. Headache, skin rashes, dizziness, blurred vision, insomnia & dysgeusia.
Drug Interactions
Increased risk of myopathy w/ CYP3A4 inhibitors eg, ciclosporin, itraconazole, ketoconazole, erythromycin, clarithromycin, HIV-PIs & nefazodone.
ATC Classification
C10AA05 - atorvastatin ; Belongs to the class of HMG CoA reductase inhibitors. Used in the treatment of hyperlipidemia.
Presentation/Packing
Form
Bestatin FC tab 40 mg
Packing/Price
50's (P1,117/box)
Form
Bestatin FC tab 20 mg
Packing/Price
50's (P804/box)
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