Cardiotaz

Cardiotaz

trimetazidine

Manufacturer:

Rainbow Life Sciences

Distributor:

TGP Pharma

Marketer:

Ambica
Full Prescribing Info
Contents
Trimetazidine HCl.
Description
Each film-coated tablet contains: Trimetazidine (as HCl) BP 35 mg (in modified release form).
Trimetazidine is a metabolic agent, a specific and selective inhibitor of enzymes of the fatty acids β-oxidation: The 3 ketoacyl CoA thiolase (3-KAT). This inhibition of β-oxidant allows a recoupling of glycolysis and an increase in glucose oxidation for better energy production under ischemic conditions.
Action
Pharmacology: Pharmacokinetics: After oral administration, maximum concentration is found on average, 5 hours after taking the tablet. Over 24 hours, the plasma concentration remains at levels >75% of the maximum concentration for 1 hour. Steady state is reached by the 60th hour, at the latest. Trimetazidine is eliminated primarily in the urine mainly in the unchanged form.
Indications/Uses
It is used in the treatment of angina pectoris and in ischemia of neurosensorial tissues in Meniere's disease.
Dosage/Direction for Use
One (1) tablet in the morning and (1) in the evening during mealtime. Or as prescribed by the physician.
Contraindications
Hypersensitivity to any of the ingredients.
Warnings
The drug is not a curative treatment for angina attacks, nor initial treatment for unstable angina pectoris, it is not a treatment for myocardial infarction. In the event of angina attack, inform the doctor.
Use In Pregnancy & Lactation
Use in Lactation: Trimetazidine is not recommended on lactating mothers.
Side Effects
Rare cases of gastrointestinal disorders (nausea and vomiting).
Drug Interactions
Co-administration with MAOI's, impaired renal and hepatic function.
Storage
Store at temperatures not exceeding 30ºC.
MIMS Class
ATC Classification
C01EB15 - trimetazidine ; Belongs to the class of other cardiac preparations.
Presentation/Packing
FC tab 35 mg x 10's.
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