Corplet

Corplet

clopidogrel

Manufacturer:

Mepro Pharmaceutical

Distributor:

Mc Graw Pharma

Marketer:

MedEthix
Concise Prescribing Info
Contents
Clopidogrel bisulfate
Indications/Uses
Alternative prophylaxis to aspirin in patients w/ atherosclerosis who are at risk of thromboembolic disorders eg, MI, peripheral arterial disease, & stroke.
Dosage/Direction for Use
Recent MI, recent stroke or established peripheral arterial disease 75 mg once daily. Patient w/ acute coronary syndrome (unstable angina/non-Q wave MI) Initially 300 mg as single loading dose & then continued at 75 mg once daily. Initiate aspirin 75-325 mg once daily & continued in combination w/ clopidogrel.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Patients w/ increased risk of bleeding eg, PUD.
Special Precautions
Patients at risk of increased bleeding from trauma, surgery, or other pathological conditions. Patients who have lesions w/ a susceptibility to bleed eg, ulcers. Use w/ drugs that might induce lesions. Severe hepatic or renal impairment. Pregnancy & lactation. Childn.
Adverse Reactions
GI hemorrhage, GI events like abdominal pain, dyspepsia, gastritis, constipation & diarrhea. Rash & skin disorders, syncope, palpitation, asthenia, hernia, cramps in legs, hypoaesthesia, neuralgia, paraesthesia, vertigo, arthritis, arthrosis, anxiety, insomnia, anemia, hemorrhagic gastritis, hemorrhagic upper GI ulcer, bilirubinemia, infectious hepatitis, & fatty liver.
Drug Interactions
Increased occult GI blood loss w/ NSAIDs. May interfere w/ the metabolism of phenytoin, tamoxifen, tolbutamide, warfarin, torsemide, fluvastatin.
MIMS Class
Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics)
ATC Classification
B01AC04 - clopidogrel ; Belongs to the class of platelet aggregation inhibitors excluding heparin. Used in the treatment of thrombosis.
Presentation/Packing
Form
Corplet FC tab 75 mg
Packing/Price
100's (P2,500/box)
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