History of cardiac decompensation, HTN or other conditions predisposing to fluid retention. GI disorder, history of GI ulceration w/ ulcerative colitis or Crohn's disease. Discontinue use if peptic ulceration or GI bleeding occur. Renal (CrCl <10 mL/min) & hepatic impairment. Not to be used in during pregnancy & lactation. Not recommended in childn. Tab
Avoid use in hepatic porphyria. Not to be administered in aspirin-sensitive asthmatic patients; preexisting asthma. Not to be given w/ aspirin tid. Inj
Monitor blood count, renal & hepatic function regularly especially during long-term treatment.