Diuzid

Diuzid

hydrochlorothiazide

Manufacturer:

Hizon

Distributor:

Willore Pharma
Concise Prescribing Info
Contents
Hydrochlorothiazide
Indications/Uses
Treatment of edema associated w/ heart failure & renal hepatic disorders. HTN, either alone or together w/ other antihypertensives eg, ACE inhibitors & β-blockers. Treatment of edema accompanying premenstrual syndrome, prevention of water retention associated w/ corticosteroids & estrogens, treatment of diabetes insipidus & prevention of renal calculus formation in patients w/ hypercalciuria.
Dosage/Direction for Use
Edema Usual dose: 25-100 mg daily, up to 200 mg daily (for severe cases). Reduced to 25-50 mg daily or intermittently. Nephrogenic diabetes insipidus Up to 100 mg daily. HTN Usual dose: 25-50 mg daily. Childn 1-2 mg/kg daily in 2 divided doses. Infant <6 mth Up to 3 mg/kg daily.
Administration
Should be taken with food.
Contraindications
Pregnancy & lactation. Patients w/ severe renal impairment or anuria, Addison's disease, preexisting hypercalcemia.
Special Precautions
Patients w/ renal impairment, existing fluid & electrolyte disturbances. Elderly. May precipitate attacks of gout, cause hyperglycemia & aggravate or unmask DM.
Adverse Reactions
Dry mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pain & cramps, seizures, oliguria, hypotension & GI disturbances. Anorexia, gastric irritation, nausea, vomiting, constipation, diarrhea, sialadenitis, headache, dizziness, photosensitivity reactions, postural hypotension, paraesthesia, impotence & yellow vision. Skin rashes, fever, pulmonary edema, pneumonitis, anaphylaxis & toxic epidermal necrolysis.
Drug Interactions
Digitalis glycosides, muscle relaxants. Corticosteroids, corticotrophin, salbutamol, carbenoxolone, amphotericin B or reboxetine. α-blockers or ACE inhibitors. Alcohol, barbiturates or opioids. Lithium, allopurinol & tetracyclines.
MIMS Class
ATC Classification
C03AA03 - hydrochlorothiazide ; Belongs to the class of low-ceiling thiazide diuretics.
Presentation/Packing
Form
Diuzid tab 12.5 mg
Packing/Price
100's (P4.9/tab)
Form
Diuzid tab 25 mg
Packing/Price
100's (P6/tab)
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in