Dynastat Description





Full Prescribing Info
Parecoxib sodium (Dynastat) 40 mg vial: Each vial contains: See table.

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For reconstitution with 2 mL of solvent. After reconstitution, the final concentration of parecoxib (Dynastat) is 20 mg/mL.
Parecoxib sodium (hereafter referred to as parecoxib) is the prodrug for the pharmacologically active moiety, valdecoxib. Following injection, parecoxib (Dynastat) is rapidly and completely hydrolyzed enzymatically to valdecoxib.
Parecoxib sodium (Dynastat) is chemically designated: N-[[4-(5-methyl-3-phenyl-4 isoxazoyl)phenyl]sulfonyl]propanamide, sodium salt. It has the chemical formula of C19H17N2O4SNa and M.W. = 392.41. CAS registry no: 198470-85-8.
Parecoxib sodium (Dynastat) is a white to off-white solid that is very soluble in water. The formulated drug product is soluble in normal (0.9%) saline at >50 mg/mL.
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