Psychotropics India


JF Draf
Concise Prescribing Info
Escitalopram oxalate
Treatment of major depressive episodes; panic anxiety disorder (social phobia); generalised anxiety disorder; obsessive-compulsive disorder; panic disorder w/ or w/o agoraphobia.
Dosage/Direction for Use
Major depressive episodes 10 mg daily. Dose may be further increased to a max of 20 mg. Panic disorder w/ or w/o agoraphobia Initially 5 mg in the 1st wk before increasing to 10 mg daily. Dose may be further increased up to a max of 20 mg daily. Generalized anxiety disorder & obsessive-compulsive disorder Initially 10 mg once daily. Max: 20 mg daily. Social anxiety 10 mg once daily for 2-4 wk. Dose may be subsequently decreased to 5 mg or increased to a max of 20 mg daily.
May be taken with or without food.
Do not use in treatment of childn & adolescents <18 yr.
Special Precautions
Increased anxiety symptoms at the start of treatment in some patients w/ panic disorder. Discontinue use when seizure or increase in seizure frequency (in patients w/ epilepsy) occurs. Patients w/ history of mania/hypomania, diabetes; or those taking oral anticoagulants or w/ known bleeding. Concomitant use w/ serotonergic drugs eg, sumatriptan or other triptans, tramadol & tryptophan; St. John's wort-containing prep. Pregnancy & lactation.
Adverse Reactions
Decreased/increased appetite, increased wt, anxiety, restlessness, abnormal dreams, decreased libido, anorgasmia, insomnia, somnolence, dizziness, paresthesia, tremor, sinusitis, yawning, nausea, diarrhea, constipation, vomiting, dry mouth, increased sweating, arthralgia, myalgia, ejaculation disorder & impotence.
Drug Interactions
Synergism w/ MAOIs. Increased anticoagulant activity of some anticoagulants including acenocoumarol & warfarin or drugs that are known to affect platelet function. May antagonize effects of antiepileptics. Increased risk of ventricular arrhythmias w/ astemizole or terfenadine. Rapid development of delirium w/ clarithromycin when added to the existing regiment of fluoxetine-nitrazepam combination; increased plasma-fluoxetine conc (by CYP450 inhibition). Caution when in concomitant w/ medicines w/ serotonergic effects eg, sumatriptans or other triptans, tramadol & tryptophan. Increased incidence of adverse reactions w/ St. John's wort-containing prep.
MIMS Class
ATC Classification
N06AB10 - escitalopram ; Belongs to the class of selective serotonin reuptake inhibitors. Used in the management of depression.
Escinal FC tab 20 mg
Escinal FC tab 10 mg
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in