Adjunct to diet & exercise in adults w/ type 2 DM. May be given as monotherapy or combination w/ other medicinal products for type 2 DM. Prevention of new or worsening heart failure or CV death, nephropathy in T2D patients. Treatment of heart failure w/ reduced ejection fraction in adult patients w/ or w/o T2D. Treatment of heart failure w/ reduced ejection fraction.
Monotherapy & add-on combination therapy 10 mg once daily. Initial combination therapy 10 mg + metformin 500 mg once daily. Heart failure 10 mg once daily & can be used in conjunction w/ other heart failure therapies.