Gludin

Gludin

metformin

Manufacturer:

MedChoice Endocrine Group

Distributor:

Metro Drug
Concise Prescribing Info
Contents
Metformin HCl
Indications/Uses
Monotherapy or in combination w/ sulphonylurea in treatment of NIDDM patients who are no longer responding to sulphonylureas.
Dosage/Direction for Use
Adult Monotherapy & combination w/ other oral antidiabetic agents Initially 500 or 850 mg 2-3 times daily. May be slowly increased by an increment of 1 tab depending on blood glucose level after 10-15 days. Max: 3 g daily in 3 divided doses. Combination w/ insulin Initially 500 or 850 mg 2-3 times daily, while insulin dosage is adjusted on the basis of blood glucose measurements. Childn ≥10 yr & adolescents Monotherapy & combination w/ insulin 500 mg daily. Max: 2 g daily in 2-3 divided doses.
Administration
Should be taken with food: Take w/ or after meals.
Contraindications
IDDM, ketoacidosis, severe infection, stress, trauma & other severe conditions w/ uncontrolled hyperglycemia. Should not be given in patients w/ severe renal or hepatic impairment. Heart failure, recent MI, dehydration, acute or chronic alcoholism & other conditions predisposing to lactic acidosis.
Special Precautions
Lactic acidosis. Should not be given to pregnant or lactating women.
Adverse Reactions
Impaired vit B12 absorption; taste disturbance; nausea, anorexia, diarrhea; pruritus, erythema, urticaria.
Drug Interactions
Risk of lactic acidosis w/ cimetidine, diuretics, alcohol & alcohol-containing medications.
MIMS Class
ATC Classification
A10BA02 - metformin ; Belongs to the class of biguanides. Used in the treatment of diabetes.
Presentation/Packing
Form
Gludin FC tab 850 mg
Packing/Price
100's (P800/box, P8/film-coated tab)
Form
Gludin FC tab 500 mg
Packing/Price
100's (P6.5/tab, P650/box)
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