Complicated skin & skin structure infections, community-acquired pneumonia including concurrent bacteremia, nosocomial pneumoniaAdult & adolescent ≥12 yr 600 mg every 12 hr for 10-14 days. Ped (birth to 11 yr) 10 mg/kg every 8 hr for 10-14 days. Vancomycin-resistant E. faecium infections including concurrent bacteremiaAdult & adolescent ≥12 yr 600 mg every 12 hr for 14-28 days. Ped (birth to 11 yr) 10 mg/kg every 8 hr for 14-28 days. Uncomplicated skin & skin structure infectionsAdult 400 mg every 12 hr for 10-14 days. Adolescent 600 mg every 12 hr for 10-14 days. Ped 5-11 yr 10 mg/kg oral every 12 hr for 10-14 days; <5 yr 10 mg/kg every 8 hr for 10-14 days.
Myelosuppression (including anemia, leukopenia, pancytopenia & thrombocytopenia). Monitor wkly complete blood count, particularly in patients receiving linezolid for >2 wk, those w/ preexisting myelosuppression, receiving concomitant drugs that produce bone marrow suppression, or w/ chronic infection who have received previous or concomitant antibiotic therapy. Discontinue in case patient develop or have worsening myelosuppression. Not to be used for patients w/ catheter-related bloodstream or catheter-site infections. Not indicated for gram -ve infections. C. difficile-associated diarrhea. Hypoglycemia; caution use in diabetic patients for potential hypoglycemic reactions.
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