Medixon

Medixon

methylprednisolone

Manufacturer:

Glorious Dexa Mandaya

Distributor:

Oxford Distributions
Concise Prescribing Info
Contents
Methylprednisolone
Indications/Uses
Treatment of adrenocortical insufficiency, collagen disease, allergic & skin inflammation, hematologic disease, hypercalcemia associated w/ cancer.
Dosage/Direction for Use
Adult 4-48 mg daily, single or multiple dose. Multiple sclerosis 160 mg for 1 wk, then 64 mg/2 days for 1 mth. Childn Adrenocortical insufficiency 0.117 mg/kg or 3.33 mg/m2/day of body surface in 3-4 divided doses. Other indication 0.417-1.67 mg/kg or 12.5-50 mg/m2/day of body surface in 3-4 divided doses.
Administration
Should be taken with food.
Contraindications
Systemic fungal infections, peptic ulcer, severe osteoporosis & patients w/ history of psychoses, herpes & those who undergo immunization procedures.
Special Precautions
Smallpox vaccination or other immunization procedures, hypothyroidism or cirrhosis, ocular herpes simplex. Closely observe patients w/ latent TB or tuberculin reactivity as reactivation of the disease may occur. Corticosteroids may mask symptoms of infection & on prolonged use may decrease resistance & inability to localize infections. Infant & childn. Pregnancy & lactation.
Adverse Reactions
Fluid & electrolyte disturbances, muscle weakness, impaired wound healing, increased BP, posterior subcapsular cataracts, growth suppression in childn, adrenal insufficiency, Cushing's syndrome, osteoporosis & peptic ulcer.
Drug Interactions
NSAIDs, antirheumatic drugs, antidiabetic drugs, smallpox vaccine & other immunizations. Barbiturates, phenytoin, rifampicin, anticholinesterase agents, K-depleting drugs.
MIMS Class
Corticosteroid Hormones
ATC Classification
H02AB04 - methylprednisolone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Presentation/Packing
Form
Medixon tab 16 mg
Packing/Price
30's (P1,188/pack)
Form
Medixon tab 4 mg
Packing/Price
100's (P990/pack)
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