Motilium

Motilium

domperidone

Manufacturer:

Johnson & Johnson

Distributor:

Zuellig
Concise Prescribing Info
Contents
Domperidone
Indications/Uses
Dyspeptic symptom complex associated w/ delayed gastric emptying, GERD, esophagitis eg, epigastric sense of fullness, early satiety, feeling of abdominal distension, upper abdominal pain; bloating, eructation, flatulence; heartburn w/ or w/o regurgitations of gastric contents in the mouth. Nausea & vomiting of functional, organic, infectious or dietetic origin or induced by radio- or drug therapy.
Dosage/Direction for Use
Chronic dyspepsia Adult 1 tab or 2 tsp tid. Childn 2.5 mL/10 kg tid. Repeat dose at bedtime if required. When results are unsatisfactory, above dosage may be doubled in adult & childn >1 yr. Nausea & vomiting Adult 2 tab or 4 tsp tid-qid. Childn 5 mL/10 kg tid-qid.
Administration
Should be taken on an empty stomach: Take 15-30 min before meals.
Contraindications
GI hemorrhage, mechanical obstruction or perforation; in patients w/ prolactin-releasing pituitary tumor (prolactinoma). Known intolerance to the drug.
Special Precautions
Hepatic impairment, renal disorders. When antacids or antisecretory agents are used concomitantly, they should be taken after meals & not before meals. Lactose intolerance. Galactosemia or glucose/galactose malabsorption. Pregnancy & lactation. Childn <1 yr.
Adverse Reactions
Increased prolactin levels. GI disorders. Transient intestinal cramps. Galactorrhea. Gynecomastia. Amenorrhea.
Drug Interactions
Antagonized by anticholinergic drugs. Antacids or antisecretory agents, CYP3A4 inhibitors.
MIMS Class
GIT Regulators, Antiflatulents & Anti-Inflammatories / Antiemetics
ATC Classification
A03FA03 - domperidone ; Belongs to the class of propulsives. Used in the treatment of functional gastrointestinal disorders.
FC tab:Non-Rx;Susp:Rx
Presentation/Packing
Form
Motilium film-coated tab 10 mg
Packing/Price
100's (P2,772/pack)
Form
Motilium oral susp 1 mg/mL
Packing/Price
100 mL x 1's (P428/bottle)
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