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Occib

Occib

celecoxib

Manufacturer:

Medhaus

Distributor:

Medhaus
Concise Prescribing Info
Contents
Celecoxib
Indications/Uses
RA, OA & ankylosing spondylitis. Management of acute pain & dysmenorrhea.
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Dosage/Direction for Use
OA 200 mg daily in 1-2 divided doses. Max: 200 mg bid. RA 100 mg bid, increased if necessary to 200 mg bid. Ankylosing spondylitis 200 mg daily in 1-2 divided doses. Max: 400 mg daily in 1-2 divided doses. Pain & dysmenorrhea Initially 400 mg followed by 200 mg if necessary on the 1st day & 200 mg bid thereafter.
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Administration
May be taken with or without food: Dose for OA/RA may be given w/ or w/o meals.
Contraindications
Hypersensitivity to celecoxib, aspirin or other NSAIDs. Patients who have demonstrated allergic type reactions to sulfonamides; or those w/ history of asthma, urticaria or allergic type reactions after taking aspirin or other NSAIDs. Treatment of peri-operative pain in the setting of CABG surgery. History of stroke (CVA), heart attack (MI), uncontrolled HTN, CHF (NYHA II-IV).
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Warnings
For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Occib detailed prescribing information
Special Precautions
Ischemic heart disease; history/active GI disease eg, ulceration; bleeding or inflammatory conditions; impaired renal & liver (Child-Pugh class B) function; dehydration; at risk for heart disease; compromised cardiac function; preexisting edema/conditions predisposing to, or worsened by fluid retention; HTN; hyperlipidemia, diabetes, smoking, peripheral arterial disease; vol-depletion. Monitor anticoagulant activity after initiating treatment. Pregnancy & lactation. Childn. Elderly.
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Adverse Reactions
Anaphylaxis, insomnia, dizziness, coughing, abdominal or chest pain, diarrhea, hallucinations, ageusia, anosmia, aseptic meningitis, vasculitis, GI hemorrhage, hepatitis, liver & acute renal failure, interstitial nephritis, hyponatremia, pruritus, rash, peripheral edema, serious skin reactions (exfoliative dermatitis, Stevens-Johnson syndrome & toxic epidermal necrolysis & drug rash w/ eosinophilia & systemic symptoms); pulmonary embolism.
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Drug Interactions
Increased risk of bleeding complications w/ warfarin. Increased plasma levels of lithium. May reduce antihypertensive effect of ACE inhibitors & AIIA. Potential for increased plasma levels w/ drugs known to inhibit P-450 2C9 or metabolized by 2D6.
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Storage
View Occib storage conditions for details to ensure optimal shelf-life.
Description
View Occib description for details of the chemical structure and excipients (inactive components).
Action
View Occib mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
ATC Classification
M01AH01 - celecoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs.
Presentation/Packing
Form
Occib cap 200 mg
Packing/Price
100's (P2,000/box)
Form
Occib cap 400 mg
Packing/Price
100's (P3,800/box)
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