Platz

Platz

clopidogrel

Manufacturer:

Endurance

Distributor:

Cathay YSS

Marketer:

Ambica
Concise Prescribing Info
Contents
Clopidogrel
Indications/Uses
Prophylaxis for thromboembolic events. Acute coronary syndromes including unstable angina & non-Q wave MI.
Dosage/Direction for Use
Acute coronary syndrome Loading dose: 300 mg followed by 75 mg daily. Prophylaxis of thromboembolic events 75 mg once daily. Management of acute coronary syndromes, unstable angina & non-Q wave MI Loading dose: 300 mg followed by 75 mg once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Active pathological bleeding eg, peptic ulcer or intracranial hemorrhage.
Special Precautions
Thrombotic thrombocytopenic purpura may occur after a short exposure (<2 wk). Patients w/ hematopoietic disorders eg, neutropenia or thrombocytopenia, hemorrhagic diathesis or other hemorrhagic disorders associated by a prolonged bleeding time or conditions w/ an increased risk of bleeding eg, GI ulcers, acute cerebral hemorrhage or severe liver dysfunction. Perform full blood counts prior to treatment & every 2 wk during 1st 3 mth of therapy & w/in 2 wk after treatment. Discontinue therapy 10-14 days before elective surgery.
Adverse Reactions
GI disturbances, skin rashes, blood dyscrasias including neutropenia & thrombocytopenia purpura, hemorrhagic disorders, hepatitis & cholestatic jaundice.
Drug Interactions
May potentiate effect of aspirin on collagen-induced platelet aggregation. Risk of increased occult GI blood loss w/ NSAIDs. May interfere the metabolism of phenytoin, tamoxifen, tolbutamide, warfarin, torsemide & fluvastatin.
ATC Classification
B01AC04 - clopidogrel ; Belongs to the class of platelet aggregation inhibitors excluding heparin. Used in the treatment of thrombosis.
Presentation/Packing
Form
Platz FC tab 75 mg
Packing/Price
100's (P1,204/box)
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