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Erythropoietin is a glycoprotein, which stimulates red blood cell production. It is produced in the kidney and stimulates the division and differentiation of committed erythroid progenitors in the bone marrow. Recombinant human erythropoietin (Epoetin alfa), a 165 amino acid glycoprotein manufactured by recombinant DNA technology, has the same biological effects as endogenous erythropoietin. It has a molecular weight of 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced. The product contains the identical amino acid sequence of isolated natural erythropoietin.
Recombinant Human Erythropoietin Alfa (Renogen) is a clear, colorless, preservative free liquid containing active ingredient erythropoietin alfa. (See table.)
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