Homozygous familial hypercholesterolemia
Starting dose: 20 mg. Max daily dose: 40 mg. Mixed dyslipidemia (Fredrickson types IIa & IIb)
Dose range: 5-40 mg. Starting dose: 10 mg. Patient requiring less aggressive LDL-C reductions or who have predisposing factors for myopathy
Initial therapy: 5 mg. Patient w/ marked hypercholesterolemia (LDL-C >190 mg/dL) & aggressive lipid targets
Starting dose: 20 mg. Patient who have not achieved the LDL-C goal
40 mg. Hypertriglyceridemia/Fredrickson type IV
Dose range: 5-40 mg. Starting dose: 10 mg. All doses to be taken as single dose anytime of the day.