Toridon

Toridon

domperidone

Manufacturer:

Torrent

Distributor:

Torrent
Concise Prescribing Info
Contents
Domperidone
Indications/Uses
Various types of dyspepsia (delayed gastric emptying time, GERD & esophagitis). Nausea & vomiting of various origins & induced by radio or drug therapy.
Dosage/Direction for Use
Nausea & vomiting Adult & adolescent ≥12 yr weighing ≥35 kg 10-20 mg tid-qid. Max: 80 mg daily for 1 wk. Dyspepsia Adult 10 mg qid. May be increased to 20 mg if necessary. Max duration: 2-4 wk.
Administration
Should be taken on an empty stomach: Take 15-30 min before meals. Disperse tab in 1 tsp of water before taking.
Contraindications
Hypersensitivity. Prolactinoma; GI hemorrhage, obstruction, perforation or conditions where gastric motility could be harmful. Co-administration w/ potent CYP3A4 inhibitors. Moderate or severe hepatic impairment.
Special Precautions
Increased risk of heart rhythm disorder & cardiac arrest. Not recommended in patients w/ known existing prolongation of cardiac conduction intervals; significant electrolyte disturbances or bradycardia; underlying cardiac disease eg, cardiac heart failure. Not recommended for chronic use or for routine prophylaxis of post-op nausea & vomiting. Renal or hepatic impairment. Pregnancy & lactation. Elderly.
Adverse Reactions
Galactorrhea or gynecomastia, amenorrhea, breast tenderness & pain, irregular menstruation & lactation disorder. Dystonic reactions. Depression, anxiety, headache, somnolence, akathisia, diarrhea, pruritus.
Drug Interactions
May antagonize the hypoprolactinaemic effect of bromocriptine & prokinetic effects w/ opioid analgesics & antimuscarinics. May increase plasma conc w/ ketoconazole. Lower bioavailability w/ antacids.
MIMS Class
GIT Regulators, Antiflatulents & Anti-Inflammatories
ATC Classification
A03FA03 - domperidone ; Belongs to the class of propulsives. Used in the treatment of functional gastrointestinal disorders.
Presentation/Packing
Form
Toridon dispertab 10 mg
Packing/Price
100's (P2,350/pack)
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