Trulicity

Trulicity

dulaglutide

Manufacturer:

Eli Lilly

Distributor:

Zuellig
Concise Prescribing Info
Contents
Dulaglutide
Indications/Uses
Adults w/ type 2 DM to improve glycaemic control as monotherapy when diet & exercise alone do not provide adequate glycaemic control in patients for whom the use of metformin is considered inappropriate due to intolerance or contraindications; or as add-on therapy w/ other glucose-lowering medicinal products including insulin, when these, together w/ diet & exercise, do not provide adequate glycaemic control.
Dosage/Direction for Use
SC Monotherapy 0.75 mg once wkly. Add-on therapy 1.5 mg once wkly. Elderly ≥75 yr Initially 0.75 mg once wkly.
Administration
May be taken with or without food.
Contraindications
Special Precautions
Not to be administered IV or IM. Not to be used in patients w/ type 1 DM or for the treatment of diabetic ketoacidosis. Not a substitute for insulin. Potential risk of dehydration, particularly in relation to GI side effects; avoid fluid depletion. Not recommended in patients w/ severe GI disease, including severe gastroparesis; end stage renal disease (<15 mL/min/1.73 m2). Discontinue if acute pancreatitis is suspected. Hypoglycaemia. CHF. Concomitant use w/ sulphonylurea or insulin. May impair ability to drive & use machines. Not recommended during pregnancy. Not to be used during lactation. Pregnancy & lactation. Childn <18 yr.
Adverse Reactions
Hypoglycaemia; nausea, diarrhoea, vomiting, abdominal pain. Decreased appetite, dyspepsia, constipation, flatulence, abdominal distention, GERD, eructation; fatigue; sinus tachycardia, 1st-degree AV block.
Drug Interactions
May impact absorption rate of oral medicinal products that requires rapid GI absorption. May slightly increase drug exposure of some PR formulations. Increased exposure w/ sitagliptin may enhance effects on blood glucose levels.
MIMS Class
ATC Classification
A10BJ05 - dulaglutide ; Belongs to the class of glucagon-like peptide-1 (GLP-1) analogues. Used in the treatment of diabetes.
Presentation/Packing
Form
Trulicity soln for inj 0.75 mg
Packing/Price
0.5 mL x 4 × 1's
Form
Trulicity soln for inj 1.5 mg
Packing/Price
0.5 mL x 4 × 1's
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