Truxim

Truxim

cefuroxime

Manufacturer:

Flamingo

Distributor:

Trumed
Concise Prescribing Info
Contents
Cefuroxime axetil
Indications/Uses
Infections due to sensitive gm +ve & gm -ve bacteria; surgical prophylaxis; more active against H. influenzae & N. gonorrhea; Lyme disease.
Dosage/Direction for Use
Adult Acute exacerbations of chronic bronchitis 250-500 mg bid for 5-7 days. Acute bronchitis 250-500 mg bid for 5-7 days. Uncomplicated gonococcal urethritis or cervicitis 1 g as single dose. Other infections 250 mg bid for 7-10 days.
Administration
Should be taken with food.
Contraindications
Special Precautions
Prolonged use may result in overgrowth of non-susceptible microorganisms. Concurrent use w/ potent diuretics. History of colitis. Monitor prothrombin time. Mild to life-threatening pseudomembranous colitis. Pregnancy.
Adverse Reactions
Anaphylaxis, angioedema, pruritus, serum sickness-like reaction, urticaria; pseudomembranous colitis; hemolytic anemia, leukopenia, pancytopenia, thrombocytopenia & increased prothrombin time. Hepatic impairment including hepatitis & cholestatic jaundice. Seizure. Erythema multiforme, Stevens-Johnson syndrome & toxic epidermal necrolysis. Renal dysfunction. Toxic nephropathy, hepatic cholestatis, aplastic anemia, hemolytic anemia, hemorrhage, increased BUN, increased CrCl, false +ve test for urinary glucose, increased alkaline phosphatase, neutropenia, elevated bilirubin & agranulocytosis.
Drug Interactions
Increase area under the serum conc w/ probenecid. Lower bioavailability w/ drugs that reduced gastric acidity.
MIMS Class
ATC Classification
J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Truxim FC tab 500 mg
Packing/Price
10's;50's
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