Valazyd

Valazyd

valsartan

Manufacturer:

Zydus Healthcare Phils

Distributor:

Metro Drug
Concise Prescribing Info
Contents
Valsartan
Indications/Uses
Management of HTN & heart failure. Reduction of CV mortality in patients w/ left ventricular dysfunction after MI.
Dosage/Direction for Use
HTN Initially 80 mg once daily, may be increased to 160 mg once daily. Max: 320 mg once daily. Heart failure Initially 40 mg bid, may be increased to 160 mg bid. Post-MI patient Start as early as 12 hr after the infarction in clinically stable patient w/ an initial dose of 20 mg bid. Dose may be doubled at intervals over the next few wk up to 160 mg bid if tolerated.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Severe hepatic impairment, biliary cirrhosis & cholestasis. Pregnancy (2nd & 3rd trimester).
Special Precautions
Monitor for hypotension. Patients w/ renal or hepatic impairment. Childn w/ CrCl <30 mL/min & those undergoing dialysis. Lactation.
Adverse Reactions
Headache, dizziness, flu symptoms, tiredness, abdominal pain, low BP, diarrhea, joint & back pain, high blood K levels, cough, decreased kidney function & rash.
Drug Interactions
Potential increased systemic exposure by inhibitors of hepatic uptake transporter OATP1B1 (eg, rifampin, cyclosporine) or hepatic efflux transporter MRP2 (eg, ritonavir). Increased serum K or creatinine (in heart failure patients) w/ K-sparing diuretics (eg, spironolactone, triamterene, amiloride), K supplements or salt substitutes containing K.
ATC Classification
C09CA03 - valsartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Valazyd FC tab 80 mg
Packing/Price
100's (P23.57/film-coated tab)
Form
Valazyd FC tab 40 mg
Packing/Price
100's (P14/film-coated tab)
Form
Valazyd FC tab 160 mg
Packing/Price
100's (P35.36/film-coated tab)
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