The majority of side-effects are gastrointestinal in origin with anorexia, nausea abdominal discomfort (pain/cramps), flatulence, vomiting and diarrhoea less frequently resulting in dehydration, dyspepsia, constipation and loose stools.
There have been reports of hearing. impairment, including hearing loss, deafness and or tinnitus in some patients receiving Azithromycin.
Interstitial nephritis and acute renal failure have been reported.
Cases of abnormal liver function including hepatitis and cholestatic jaundice have been reported.
Reductions in neutrophil counts have occasionally been observed.
There have been rare reports of taste disturbances.
Asthenia and paraesthesia have been reported although a causal relationship may not have been established.
The following adverse effects have occurred: Chest pain, melena, nephritis, vaginitis, headache, dizziness, convulsions, vertigo, somnolence and fatigue.
Palpitations and arrythmias including ventricular tachycardia have been reported although a causal relationship with Azithromycin has not been established.
Allergic reactions including arthralgia, oedema, urticaria, rash, photosensitivity, angioedema and anaphylaxis (less frequently fatal) have occurred. Less frequently, serious skin reactions including erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis have occurred.