Zinnat

Zinnat

cefuroxime

Manufacturer:

Duncan

Distributor:

Zuellig

Marketer:

GlaxoSmithKline
Concise Prescribing Info
Contents
Cefuroxime axetil
Indications/Uses
Lower & upper resp tract, GUT, skin & soft tissue infections; gonorrhea including acute uncomplicated gonococcal urethritis & cervicitis. Treatment & prevention of early & late Lyme disease.
Dosage/Direction for Use
Tab Adult Most infections, UTI, mild to moderate lower resp tract infections (eg, bronchitis), pyelonephritis 250 mg bid. More severe lower resp tract infections or pneumonia (if suspected) 500 mg bid. Uncomplicated gonorrhea 1 g single dose. Lyme disease Adult & childn >12 yr 500 mg bid for 14 days. Childn Most infections 125 mg bid. Otitis media or severe infections 250 mg bid. <12 yr Lyme disease 250 mg bid for 14 days. Oral susp Childn 12 yr-3 mth & infant Most infections 10 mg/kg bid, max: 250 mg daily. Otitis media or more severe infections 15 mg/kg bid, max: 500 mg daily for 14 days.
Administration
Should be taken with food: Take immediately after meals for optimum absorption.
Contraindications
Hypersensitivity to cephalosporins & other β-lactams.
Special Precautions
Hypersensitivity to penicillins & other β-lactams. Pseudomembranous colitis. Diabetics & phenylketonurics. Prolonged use. May impair the ability to drive or operate machinery. Pregnancy & lactation. Tab: Jarisch-Herxheimer reaction.
Adverse Reactions
Overgrowth of Candida; eosinophilia; headache, dizziness; GI disturbances including diarrhea, nausea, abdominal pain; transient increases of hepatic enzyme levels (ALT/AST, LDH).
Drug Interactions
Lower bioavailability w/ antacid; estrogen reabsorption & reduced efficacy w/ OCs.
MIMS Class
Cephalosporins
ATC Classification
J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Zinnat FC tab 250 mg
Packing/Price
24's
Form
Zinnat FC tab 500 mg
Packing/Price
24's
Form
Zinnat granules for oral susp 125 mg
Packing/Price
(sachet) 4.22 g x 10 × 1's
Form
Zinnat granules for oral susp 125 mg/5 mL
Packing/Price
50 mL x 1's;70 mL x 1's
/philippines/image/info/zinnat granules for oral susp 125 mg-5 ml/125 mg-5 ml x 50 ml?id=58122d33-e105-442b-92b4-a282009be167
/philippines/image/info/zinnat granules for oral susp 125 mg-5 ml/125 mg-5 ml x 70 ml?id=8b35c0ca-6127-4026-bc61-a282009be167
Form
Zinnat granules for oral susp 250 mg/5 mL
Packing/Price
50 mL x 1's
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