Dapril

Dapril

lisinopril

Manufacturer:

Medochemie

Distributor:

Medochemie
Concise Prescribing Info
Contents
Lisinopril
Indications/Uses
Treatment of essential & renovascular HTN, alone or in combination w/ other antihypertensives; CHF not controlled adequately by digitalis & diuretic therapy.
Dosage/Direction for Use
Essential HTN Initially 10 mg. Maintenance: 20 mg/day. Max: 80 mg/day. Renovascular HTN Initially 2.5 or 5 mg, may be adjusted according to BP response. CHF not adequately controlled by diuretics &/or digitalis Initially 2.5 mg. Usual dose: 5-20 mg. Renal impairment Starting dose: CrCl ≤30 mL/min & ≥10 mL/min 5 mg, <10 mL/min, including patient on dialysis 2.5 mg. Max: 40 mg. All doses should be given once daily as a single dose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Concomitant use w/ aliskiren-containing products in patients w/ DM or renal impairment (GFR <60 mL/min/1.73 m2).
Special Precautions
Dual blockade of the renin-angiotensin-aldosterone system; symptomatic hypotension; renal function impairment; angioneurotic oedema; patients undergoing major surgery or during anaesth w/ agents that produce hypotension. Pregnancy & lactation. Childn. Elderly.
Adverse Reactions
Dizziness, headache, diarrhoea, fatigue; cough, nausea, rash, hypotension, orthostatic effects, palpitation, chest pain, asthenia.
Drug Interactions
Decreased renal function (including acute renal failure) w/ ACE inhibitors, ARBs or aliskiren. Potentiation w/ diuretics. May diminish efficacy w/ indomethacin. Concomitant use of K-sparing diuretics (eg spironolactone, triamterene or amiloride) or K supplements. Increase of serum K w/ K supplements & K-sparing diuretics.
ATC Classification
C09AA03 - lisinopril ; Belongs to the class of ACE inhibitors. Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Dapril tab 10 mg
Packing/Price
100 × 10's;3 × 10's
Form
Dapril tab 5 mg
Packing/Price
3 × 10's
Form
Dapril tab 20 mg
Packing/Price
100 × 10's;3 × 10's
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