vaccine, rabies


Chiron Behring


Concise Prescribing Info
Inactivated rabies virus (derived from strain Flury LEP) ≥2.5 IU
Pre- & post-exposure immunization against rabies.
Dosage/Direction for Use
IM 1 mL/dose. Administer by IM inj into the deltoid muscle, or into the anterolateral region of the thigh in small childn. Pre-exposure immunization 1 dose on days 0, 7 & 21 (or 28). Post-exposure immunisation Unimmunised or incompletely immunised individuals 1 single dose on days 0, 3, 7, 14, 28. Alternatively, 2 doses on day 0 (as 1 dose into the right & left deltoid muscle, or in small childn, each into the anterolateral region of the right & left thigh), & 1 dose each on days 7 & 21. Previously fully immunized individuals 2 doses, 1 on each of days 0 & 3 (independent of interval to last immunization). Immunocompromised individuals Administer once on days 0, 3, 7, 14, 28. Initial dose (day 0) should be doubled w/ a single dose post-exposure. Intradermal inj 0.1 mL/dose. Administer in the upper arm over the deltoid. Non-vaccinated individuals 1 dose over each left & right deltoid on days 0, 3, 7, & 1 dose on upper arm on day 28 (or 30) & day 90. Alternatively, dose for day 90 can be administered as a 2nd dose on day 28 or 30. Fully vaccinated individuals Immediate booster dose on days 0, 3.
Hypersensitivity. Avoid pre-exposure immunisation in individuals w/ acute disorders requiring treatment.
Special Precautions
Do not administer intravascularly & in the gluteal muscle. Patients w/ allergies to chicken protein or exhibit positive reaction in the chicken protein skin test. Hypersensitivity to antibiotics amphotericin B, chlortetracycline, neomycin. Do not administer as intradermal inj in individuals receiving long-term corticosteroid or other immunosuppressive therapy or chloroquine; & in immunocompromised individuals. Pregnancy & lactation.
Adverse Reactions
Inj site reactions eg, pain, redness, swelling, induration. Fever, headache, myalgia, lymph node swelling, fatigue, arthritis, GI disorders.
Drug Interactions
Immunosuppressives & antimalarials. Rabies Ig.
ATC Classification
J07BG01 - rabies, inactivated, whole virus ; Belongs to the class of rabies viral vaccines.
ChiroRab vaccine inj
1 mL x 1's
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