Cholemax

Cholemax

ursodeoxycholic acid

Manufacturer:

MacroPhar

Distributor:

MacroPhar Lab
Concise Prescribing Info
Contents
Ursodeoxycholic acid
Indications/Uses
Dissolution of radiolucent cholesterol gallstones <20 mm in diameter. Prevention of gallstone formation in obese patients undergoing rapid wt loss.
Dosage/Direction for Use
Gallstone dissolution 8-10 mg/kg/day in 2 or 3 divided doses. Prevention of gallstone 300 mg bid.
Administration
Should be taken with food.
Contraindications
Hypersensitivity to ursodeoxycholic acid or bile acid. Calcified cholesterol stones, radiopaque stones or radiolucent bile pigment stones. Patients w/ compelling reasons for cholecystectomy including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis or biliary-GI fistula.
Special Precautions
Measure AST & ALT at initiation of & during therapy. Perform ultrasound of gallbladder at 6-mth interval for 1st yr of therapy. Pregnancy & lactation.
Adverse Reactions
Abdominal pain, viral infection, headache, dyspepsia, upper resp tract infection, nausea, sinusitis, constipation, vomiting, pharyngitis, arthralgia, flatulence, back pain, cough, bronchitis, UTI, arthritis, myalgia, allergy, cholecystitis, rhinitis, fatigue. Diarrhea, dizziness, influenza-like symptoms, musculoskeletal pain, dysmenorrhea, alopecia, sinusitis.
Drug Interactions
Decreased absorption w/ Al-containing antacids, bile acid sequestrants. May reduce efficacy because of increased hepatic cholesterol secretion w/ clofibrate, estrogen, hormonal contraceptives.
ATC Classification
A05AA02 - ursodeoxycholic acid ; Belongs to the class of bile acids. Used in bile therapy.
Presentation/Packing
Form
Cholemax 250 mg cap
Packing/Price
10 × 10's;10's
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