Floctil

Floctil

azithromycin

Manufacturer:

Unison

Distributor:

Medline
Concise Prescribing Info
Contents
Azithromycin dihydrate
Indications/Uses
Upper & lower resp tract infections, skin & soft tissue infections, otitis media, uncomplicated genital infections due to Chlamydia trachomatis & non-multiresistant Neisseria gonorrhoeae.
Dosage/Direction for Use
Cap 500 mg once daily for 3 days. Adult STD caused by Chlamydia trachomatis or susceptible Neisseria gonorrhoeae 1 g as a single dose. Susp Otitis media Childn ≥6 mth Initially 30 mg/kg as a single dose. Max: 1,500 mg. Alternatively, 10 mg/kg once daily for 3 days. Max: 500 mg/day; or 10 mg/kg on Day 1. Max: 500 mg/day, followed by 5 mg/kg once daily on Days 2-5. Max: 250 mg/day. Pharyngitis & tonsillitis 12 mg/kg once daily for 5 days. Community acquired pneumonia Infants >3 mth & childn Mild infection or step down therapy: 10 mg/kg on Day 1. Max: 500 mg/day, followed by 5 mg/kg once daily on Days 2-5. Max: 250 mg/day.
Administration
Cap: Should be taken on an empty stomach: Take at least 1 hr before or 2 hr after meals or Al- & Mg-containing antacids.|Oral susp: May be taken with or without food: May be taken w/ meals to reduce GI discomfort.
Contraindications
Hypersensitivity to azithromycin, erythromycin, other macrolides.
Special Precautions
Hypersensitivity. Preexisting liver disease; hepatocellular &/or cholestatic hepatitis w/ or w/o jaundice; hepatic necrosis, failure & death. QTc prolongation & ventricular arrhythmias, including Torsades de pointes. Prolonged use may result to fungal or bacterial superinfection including C. difficile-associated diarrhea. Severe liver & renal impairment. Pregnancy & lactation.
Adverse Reactions
Nausea, abdominal discomfort, vomiting, flatulence, diarrhea, dizziness, headache, somnolence, paraesthesia, convulsions, arthralgia, liver dysfunction, hearing impairment (reversible). Susp: Increased liver enzymes, prolonged QT interval, Torsades de pointes.
Drug Interactions
May increase serum levels of carbamazepine, phenytoin, theophylline, cyclosporine. Decreased plasma conc by antacid. Increased risk of bleeding w/ warfarin. Digoxin toxicity (eg, vomiting, cardiac arrhythmias) w/ digoxin. Increased risk of acute ergotism w/ ergot derivatives.
MIMS Class
ATC Classification
J01FA10 - azithromycin ; Belongs to the class of macrolides. Used in the systemic treatment of infections.
Presentation/Packing
Form
Floctil susp 100 mg/5 mL
Packing/Price
1's
Form
Floctil susp 200 mg/5 mL
Packing/Price
1's
Form
Floctil cap 250 mg
Packing/Price
1 × 6's;10 × 6's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in