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Goofice

Goofice

Manufacturer:

Eisai

Distributor:

DKSH
Concise Prescribing Info
Contents
Elobixibat
Indications/Uses
Chronic constipation (except for constipation associated w/ organic diseases).
Dosage/Direction for Use
Adult 10 mg once daily. Max dose: 15 mg daily.
Administration
Should be taken on an empty stomach.
Contraindications
Hypersensitivity. Patients w/ documented intestinal obstruction associated w/ tumor or hernia or suspicion of such conditions.
Special Precautions
Drug- & disease-induced constipations. Consider dose reduction, drug w/drawal, or discontinuation if abdominal pain or diarrhoea occurs. Serious liver disorder (eg, biliary obstruction or reduced bile acid secretion). Pregnancy & lactation; discontinue breastfeeding during treatment. Elderly. Low birth wt infants, neonate, nursing infants, infants or ped patients.
Adverse Reactions
Abdominal pain, diarrhoea, lower abdominal pain & abdominal distension. Abnormal liver function test, increased ALT (GPT) & AST (GOT); nausea, upper abdominal pain, abdominal discomfort, soft faeces; increased creatine kinase & creatine phosphokinase.
Drug Interactions
May interfere w/ reabsorption of bile acid prep (eg, ursodeoxycholic acid, chenodeoxycholic acid). May attenuate the effects w/ Al-containing antacids (eg, sucralfate hydrate, aldioxa), cholestyramine & colestimide. May elevate & enhance effects of digoxin, dabigatran, etexilate methanesulfonate. May decrease blood levels & effects of midazolam.
ATC Classification
A06AX - Other drugs for constipation ; Used in the treatment of constipation.
Presentation/Packing
Form
Goofice FC tab 5 mg
Packing/Price
100's
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