Administer by IV infusion. Duration: 15 min. Adult & adolescent >50 kg
1,000 mg max single dose. Max daily dose: 4 g. Min interval between each administration should not be <4 hr. 1-4 infusions during the 1st 24 hr since the onset of pain syndrome (post-op). May be extended, if necessary, but should not exceed total duration of 72 hr & total of 12 infusions. Childn 10-50 kg
15 mg/kg. Max daily dose: 60 mg/kg. Min interval between each administration daily dose must not be <4 hr. Do not exceed infusion/day. Renal insufficiency (CrCl ≤30 mL/min)
Interval must be increased up to 6 hr & max duration must not exceed 48 hr.