Metrolex Dosage & Drug Information

Concise Prescribing Info

Contents

Metronidazole

Indications/Uses

Listed in Dosage.

Dosage/Direction for Use

Tab Trichomoniasis, amoebiasis, giardiasis, acute ulcerative gingivitis. Treatment & prevention of post-op anaerobic infections. Amoebic dysentery & other intestinal amoebic disease 200 mg tid for 7 consecutive days or 2 g as a single dose or 800 mg morning & 1.2 g evening for 2 days. Amoebic dysentery & other intestinal amoebic disease Adult 500-750 mg tid for 5-10 days. Childn 11.6-16.7 mg/kg tid for 10 days. Inj Treatment & prevention of infections caused by susceptible anaerobic bacteria Adult & childn >12 yr Loading dose of 15 mg/kg infused over 1 hr, maintenance: 7.5 mg/kg infused over 1 hr 6-8 hrly.

Administration

Should be taken with food.

Contraindications

Blood dyscrasias. Active CNS disease.

Special Precautions

1st trimester of pregnancy, lactation.

Adverse Reactions

GI discomfort, anorexia, coated tongue, dry mouth, unpleasant taste, headache, pruritus, skin rash. Rarely, vomiting, diarrhea, neurologic effects, urethral discomfort & darkening of urine. Leukopenia. Peripheral neuropathy.

View ADR Monitoring Form

Drug Interactions

Alcohol, may provoke a disulfiram-like reaction. Metronidazole enhances the anticoagulant effect of warfarin.

MIMS Class

Antiamoebics / Other Antibiotics / Preparations for Vaginal Conditions

ATC Classification

P01AB01 - metronidazole ; Belongs to the class of nitroimidazole derivatives antiprotozoals. Used in the treatment amoebiasis and other protozoal diseases.
J01XD01 - metronidazole ; Belongs to the class of imidazole derivative antibacterials. Used in the systemic treatment of infections.

Thai FDA Category

Presentation/Packing

Form

Metrolex inj 0.5 %

Packing/Price

100 mL x 1's

Form

Metrolex tab 400 mg

Packing/Price

10 × 10's;50 × 10's

Form

Metrolex tab 200 mg

Packing/Price

10 × 10's;50 × 10's

Metrolex

metronidazole

Manufacturer:

Siam Bheasach

Distributor:

Siam Pharmaceutical