Morfarin

Morfarin

warfarin

Manufacturer:

Charoon Bhesaj

Distributor:

Charoon Bhesaj
Concise Prescribing Info
Contents
Warfarin Na
Indications/Uses
Prophylaxis & treatment of venous thrombosis, pulmonary embolism & thrombolic disorders. Prophylaxis of thromboembolic complication associated w/ atrial fibrillation. Adjunct in prophylaxis of systemic embolism after MI.
Dosage/Direction for Use
Initially 2-5 mg/day. Maintenance: 2-10 mg/day. Duration of therapy is individualized.
Administration
May be taken with or without food.
Contraindications
Hemorrhagic tendencies or blood dyscrasias; neurosurgery; recent eye, brain or spinal cord surgery; GIT, resp or GUT bleeding; aneurysm; pericarditis & pericarditis effusion; bacterial endocarditis; spinal puncture; lumbar block anesth. Severe hepatic or renal disease, severe HTN, endocarditis, visceral carcinoma. Pregnancy.
Special Precautions
Protein C & protein S deficiency associated w/ tissue necrosis. Concomitant NSAIDs. Elderly, childn ≤18 yr.
Adverse Reactions
Hemorrhagic skin necrosis, paralysis; paresthesia; headache; chest, abdomen, joint, muscle or other pain; dizziness; shortness of breath; difficult breathing or swallowing; unexplained swelling; weakness; hypotension; unexplained shock; necrosis of skin & other tissues; alopecia; various kinds of skin rashes.
Drug Interactions
Drugs that affect prothrombin time. Increased effect: Acetaminophen, androgens, capecitabine, cephalosporins, disulfiram, fibric acids, glucagon, NSAIDs, COX-2 selective, propoxyphene, quinolones, SSRIs, sulfonamides, thyroid hormones, zafirlukast, zileuton, allopurinol, amiodarone, antifungals, cimetidine, HMG-CoA reductase inhibitors, metronidazole, omeprazole, propafenone, quinidine, macrolides, tetracyclines, vit E. Decreased effect: OC, estrogens, griseofulvin, aminogluthimide, barbiturates, carbamazepine, glutethimide.
ATC Classification
B01AA03 - warfarin ; Belongs to the class of vitamin K antagonists. Used in the treatment of thrombosis.
Presentation/Packing
Form
Morfarin tab 3 mg
Packing/Price
(foil) 50 × 10's
Form
Morfarin tab 5 mg
Packing/Price
(foil) 50 × 10's
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