Normetec

Normetec

Manufacturer:

Pfizer

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Per 5 mg/20 mg FC tab Amlodipine besylate 5 mg, olmesartan medoxomil 20 mg. Per 5 mg/40 mg FC tab Amlodipine besylate 5 mg, olmesartan medoxomil 40 mg. Per 10 mg/40 mg FC tab Amlodipine besylate 10 mg, olmesartan medoxomil 40 mg
Indications/Uses
Essential HTN in patients inadequately controlled by olmesartan medoxomil or amlodipine monotherapy.
Dosage/Direction for Use
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to dihydropyridine derivatives. Severe hepatic insufficiency & biliary obstruction. Cardiogenic shock, acute MI (w/in 1st 4 wk), unstable angina pectoris. Pregnancy & lactation.
Special Precautions
Renal & hepatic impairment; correct hypovolaemia or Na depletion prior to administration. Severe CHF or underlying renal disease including renal artery stenosis. Renovascular HTN, recent kidney transplantation. Monitor serum K & creatinine. Aortic or mitral valve stenosis; obstructive hypertrophic cardiomyopathy. Primary aldosteronism. Ischaemic heart or cerebrovascular disease. May impair ability to drive or operate machinery. Childn & adolescent <18 yr.
Adverse Reactions
Dizziness, headache, peripheral oedema, oedema, pitting oedema, fatigue, angina pectoris, bronchitis, pharyngitis, rhinitis, abdominal pain, gastroenteritis, arthritis, skeletal pain, haematuria, UTI, chest pain, influenza-like symptoms, pain, flushing.
Drug Interactions
K supplements, K-sparing diuretics, salt substitute containing K, heparin, ACE inhibitors, lithium, other hypertensives (eg, α-blockers, diuretics), NSAIDs including COX-2 inhibitors, acetylsalicylic acid & nonselective NSAIDs, antacid (Al-Mg hydroxide), diltiazem, ketoconazole, itraconazole, ritonavir, carbamazepine, phenobarb, phenytoin, fosphenytoin, primidone, rifampicin, Hypericum perforatum, sildenafil.
MIMS Class
Angiotensin II Antagonists / Anti-Anginal Drugs / Calcium Antagonists
ATC Classification
C09DB02 - olmesartan medoxomil and amlodipine ; Belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers. Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Normetec FC tab 10 mg/40 mg
Packing/Price
30's
Form
Normetec FC tab 5 mg/20 mg
Packing/Price
30's
Form
Normetec FC tab 5 mg/40 mg
Packing/Price
30's
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